Title of article
New route for the synthesis of thieno[2, 3- d]pyrimidine derivatives
Author/Authors
Shaabani, Tayyebe Department of Chemistry - Khuzestan Science and Research Branch, Islamic Azad University, Ahvaz, Iran , Nikpour, Mohsen Department of Chemistry - Khuzestan Science and Research Branch, Islamic Azad University, Ahvaz, Iran
Pages
3
From page
2035
To page
2037
Abstract
Condensation of ethylthioglycolate with 2,4-dichloro-6-phenylpyrimidine-5-carbonitrile afforded ethyl 5-amino-2-chloro-4-phenylthieno[2,3-d]pyrimidine-6-carboxylate in alkalineethanol. Chlorine atom of the latter compound was easily replaced by secondary amines in ethanol to achieve a new group of ethyl5-amino -4-phenylthieno[2,3-d]pyrimidine-6-carboxylate derivatives.
Keywords
Ethylthioglycolate , 2,4-Dichloro-6-phenylpyrimidine-5-carbonitrile , Ethyl-5-amino-2-chloro-4-phenylthieno[2,3-d]pyrimidine-6-carboxylate , Substitution , Cyclocondensation
Journal title
Astroparticle Physics
Serial Year
2017
Record number
2435981
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