Title of article :
One-pot and chemoselective synthesis of bis(4-hydroxycoumarin) derivatives catalyzed by nano silica chloride
Author/Authors :
Karimian, Ramin Baqiyatallah University of Medical Sciences, Tehran , Piri, Farideh Department of Chemistry - Faculty of Science - Zanjan University, Zanjan , Safari, Ali Asghar Department of Chemistry - Faculty of Sciences - Zanjan Branch - Islamic Azad University, Zanjan , Davarpanah, Javad Baqiyatallah University of Medical Sciences, Tehran
Abstract :
Nano silica chloride (nano SiO2Cl) has been found to be an efficient, chemoselective and recyclable catalyst for
facile and simple condensation of 4-hydroxycoumarin with aromatic and heteroaromatic aldehydes into
bis(4-hydroxycoumarin)methanes in dry CH2Cl2. The products were obtained in high to excellent yields.
Keywords :
4-hydroxycoumarin , Knoevenagel condensation , Michael addition , bis(4-hydroxycoumarin)methane , Chemoselective , Recyclable , Nano silica chloride
Journal title :
Astroparticle Physics
