Title of article :
Microwave-assisted solvent-free synthesis of 1H-indole-2,3-dione derivatives catalyzed by lanthanum(III) chloride heptahydrate
Author/Authors :
Abdolmohammadi, Shahrzad Department of Chemistry - East Tehran Branch, Islamic Azad University, Tehran, Iran , Makipour, Peymaneh Department of Chemistry - East Tehran Branch, Islamic Azad University, Tehran, Iran , Shariati, Minoo Department of Chemical Engineering - Tafresh University, Tafresh, Iran
Abstract :
We report on the preparation of a series of 1H-indole-2,3-diones (isatins) a new microwave-assisted solvent-free approach using lanthanum trichloride heptahydrate (LaCl3.7H2O) as an efficient heterogeneous catalyst. These biologically important compounds were prepared via a condensation reaction of anilines with oxalic acid. The use of inexpensive and reusable catalyst under MWI conditions, and with easier isolation of the products in high yields makes this protocol eco-friendly and versatile compared to the existing procedures.
Keywords :
Anilines , 1H-Indole-2,3-diones (Isatins) , Lanthanum trichloride heptahydrate (LaCl3.7H2O) , Microwave-assisted , Oxalic acid , Reusability of catalyst , Solvent-free conditions
Journal title :
Astroparticle Physics
