Author/Authors :
Goodarzi, Zohreh Department of Chemical Engineering - Faculty of Engineering - Ferdowsi University of Mashhad, Mashhad , Maghrebi, Morteza Department of Chemical Engineering - Faculty of Engineering - Ferdowsi University of Mashhad, Mashhad , Fakhari Zavareh, Alireza Department of Chemistry - Faculty of Science - Shahid Beheshti University, Tehran , Mokhtari-Hosseini, Zahra-Beagom Faculty of Petroleum and Petrochemical Engineering - Hakim Sabzevari University, Sabzevar , Ebrahimi-hoseinzadeh, Bahman Department of Life Sciences Engineering - Faculty of New Sciences and Technologies - University of Tehran, Tehran , Hatamian Zarmi, Ashrafasadat Department of Life Sciences Engineering - Faculty of New Sciences and Technologies - University of Tehran, Tehran , Barshan-tashnizi, Mohammad Department of Life Sciences Engineering - Faculty of New Sciences and Technologies - University of Tehran, Tehran
Abstract :
An electrochemical sensor was prepared to detect
nicotine by depositing copper nanoparticles (Cu NPs)
on the surface of a glassy carbon electrode (GCE) modified
with multi-walled carbon nanotubes (MWNTs). The modified
electrode was characterized by scanning electron microscopy
and cyclic voltammetry. The novel-modified
sensor exhibited effective electrocatalytic activities toward
anodic oxidation of nicotine. Calibration plot showed two
linear regions with different sensitivity, 1.121 (r2 = 0.982)
in the range from 1 9 10-6 to 9 9 10-5 M and 0.164
(r2 = 0.982) from 1 9 10-4 M up to 1 9 10-3 M. The
detection limit was 1 lM. For six parallel detections of
1 mM nicotine, the relative standard deviation was 5.68 %,
suggesting that the film-modified electrode had good reproducibility.
Experimental parameters affecting the sensor
response such as pH, modifier concentration and electrodeposition
scan rate were found to be optimum at 7.0,
2 mg mL-1 and 80 mV s-1, respectively.
Keywords :
Copper nanoparticles , Cyclic voltammetry , Multi-walled carbon nanotube , Nano-biosensor , Nicotine
