Title of article :
Three component one pot synthesis of 1-N, 7-N-bisethoxyphthalimido-4-(3,5-dimethyl-4-substitutedphenyl-4,7-dihydro-1H-dipyrazolo[3,4-b;4',3'-e]pyridin-8-yl)-benzothiazole
Author/Authors :
Hussain, Nasir Synthetic organic chemistry research laboratory - Department of chemistry - Pacific college of basic and applied sciences - PAHER - University Udaipur (Raj.), India , Chittora, Anil Kumar Department of Basic Science - College of Technology and Engineering, MPUAT, Udaipur , Vaghasiya, Hitesh Vinodbhai Synthetic organic chemistry research laboratory - Department of chemistry - Pacific college of basic and applied sciences - PAHER - University Udaipur (Raj.), India , kasturi, Amar Kumar Synthetic organic chemistry research laboratory - Department of chemistry - Pacific college of basic and applied sciences - PAHER - University Udaipur (Raj.), India , Mishraa, Anurag Synthetic organic chemistry research laboratory - Department of chemistry - Pacific college of basic and applied sciences - PAHER - University Udaipur (Raj.), India , Sharma, Akhilesh Synthetic organic chemistry research laboratory - Department of chemistry - Pacific college of basic and applied sciences - PAHER - University Udaipur (Raj.), India
Abstract :
In the three component one pot synthesis 5-methyl-2,4-dihydro-3H-pyrazole-3-one reacted with substituted aldehydes and 2-Aminobenzothiazole to produce 4-{3,5-dimethyl-4-(substitutedphenyl)-4,7-dihydro-1H-dipyrazolo[3,4-b;4’,3’-e]pyridin-8-yl}-benzothiazole (4a-e). Condensation of (4a-e) with two mole of Bromoethoxyphthalimide in ethanol using NaH as a base give 1-N,7-N-bisethoxyphthalimido-4-(3,5-dimethyl-4-substitutedphenyl-4,7-dihydro-1H-dipyrazolo[3,4-b;4’,3’-e]pyridine-8-yl)-aminobenzo thiazole (5a-e). Structure of the synthesized compounds was confirmed on the basis of elemental analyses and spectral studies.
Keywords :
Substituted aldehydes , Bromoethoxyphthalimide , NaH , Pyrazole , Benzothiazole
Journal title :
Astroparticle Physics
