Title of article :
Catalyst-free synthesis of thiazole derivatives in water
Author/Authors :
Shafiee, Shahin Danayan Fara Kimiya (DFK)company, Shahin Shahr, Isfahan, Iran.
Abstract :
Functionalized thiazoles are generated from the reaction of dimethyl acetylenedicarboxylate, benzoylisothiocyanates and primary amines and trialkyl phosphite in water. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.
Keywords :
Thiazoles , Phosphonate , Primary amines , Phosphites , Activated acetylenic compound , Benzoylisothiocyanates
Journal title :
Astroparticle Physics
