Title of article :
Aflatoxins in Iran: Nature, Hazards and Carcinogenicity
Author/Authors :
Khoshpey,B School of Public Health - Tehran University of Medical Sciences, Tehran , Farhud, DD School of Public Health - Tehran University of Medical Sciences, Tehran , Zaini, F School of Public Health - Tehran University of Medical Sciences, Tehran
Abstract :
Many studies have shown that mycotoxin contamination of agricultural products is a challenge for individual’s health especially
in developing countries. Improper production and storage of foods, prepare conditions for aflatoxin production in
crops, especially rice, wheat, pistachio, walnut, almond, etc which are the main sources of foods for people. Feeding livestock
by contaminated bread is another way of human exposure to mycotoxins, especially aflatoxin and because of expensive
methods for detecting and analyzing aflatoxin in laboratory; it is not measured in foods. This manuscript is a review of
some Iranian and nonIranian reports about aflatoxin, its exposure ways, its adverse effect on human health and nutrition, as
well as methods for reducing its exposure. Based on studies on foods, aflatoxin exposure is high in Iran. Since livestock
feeding by contaminated bread is one of the potential ways for milk contamination, we should control and reduce aflatoxin
contamination by improving production process, storage condition and livestock feeding as soon as possible. Pistachio is
one of the most important exporting products of Iran and to maintain Iran’s position in exporting of this product, specific
regulations on lowering its contamination with aflatoxin should be considered seriously. Finally, effective controlling of all
food and feedstuffs which are vulnerable to aflatoxin contamination is necessary to prevent its effects.
Keywords :
Aflatoxicosis , Mycotoxins , Teratogenicity , Oxidative stress , Cytochrome P450 , Congenital malformations , Iran
Journal title :
Astroparticle Physics