Author/Authors :
Dogan, Sumeyra Department of Pediatric Radiology - Trakya University, Faculty of Medicine, Edirne, Turkey. , Dogan, Mehmet S Department of Pediatric Radiology - Trakya University, Faculty of Medicine, Edirne, Turkey. , Tutunculer, Filiz Department of Pediatric Endocrinology - Faculty of Medicine - Trakya University, Edirne, Turkey , Yapici Ugurlar, Ozge Department of Pediatric Radiology - Trakya University, Faculty of Medicine, Edirne, Turkey. , Genchellac, Hakan Department of Pediatric Radiology - Trakya University, Faculty of Medicine, Edirne, Turkey.
Abstract :
Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing's syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant with brain atrophy and myelination delay that might be due to iatrogenic Cushing's syndrome caused by topical corticosteroid use.
Keywords :
Diaper dermatitis , iatrogenic Cushing’s syndrome , brain atrophy , myelination , magnetic resonance imaging