Author/Authors :
Abdi, Seifolah Cardiovascular Intervention Research Center - Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences , Amiri, Faramarz Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, I.R. Iran , Shafe, Omid Cardiovascular Intervention Research Center - Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences , Ebrahmi Rad, Reza Azad Islamic University Complex - Tonekabon Mazandaran, I.R. Ira , Fakhreddin, Hamid Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, I.R. Iran , Jebeli, Alireza Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, I.R. Iran , Sayadmanesh, Abdullah Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, I.R. Iran , Shadmani, Moslem Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, I.R. Iran , Ghobadi, Ebrahim Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, I.R. Iran
Abstract :
Background: Carotid artery stenosis accounts for 10% of all ischemic strokes. Carotid
endarterectomy (CEA) and carotid artery stenting (CAS) are currently the treatment for
stroke prevention.
Methods: We sought to compare the efficacy and safety of each treatment in patients with carotid
artery stenosis. After treatment, the patients were evaluated regarding their outcomes during
the 1st and 6th postprocedural months.
Result: Sixty-nine patients (45 male [65.2%] and 24 female [24.8%]) at a mean age of 63.85 ±
14.17 years were enrolled. In 12 (17.4%) patients, both left and right carotid arteries were
stenotic. Neither CEA nor CAS had in-hospital and procedural complications. However, in
longer-term follow-up, transient ischemic attack occurred in 2 (2.9%) patients in the CEA
group, while significant in-stent restenosis occurred in 2 (2.9%) patients after CAS.
Multivariate analysis showed no association between smoking, coronary artery disease,
dyslipidemia, hypertension, diabetes mellitus, and age and stent stenosis (P = 0.9, P = 0.9,
P = 0.5, P = 0.6, P = 0.8, and P = 0.1, correspondingly).
Conclusions: Both CEA and CAS are approved therapeutic strategies for the treatment of carotid
artery stenosis. Low complications and good results can be expected if case selection is done
according to the current guidelines.
