Author/Authors :
Shakerian, Farshad Cardiovascular Intervention Research Center -Rajaie Cardiovascular, Medical, and Research Center -Iran University of Medical Sciences, Tehran, I.R. Iran , Sadr-Ameli, mohammad ALi Cardiovascular Intervention Research Center -Rajaie Cardiovascular, Medical, and Research Center -Iran University of Medical Sciences, Tehran, I.R. Iran , Alsadat Mousavi, Maryam Rajaie Cardiovascular - Medical, and Research Center - Iran University of Medical Sciences, Tehran, I.R. Iran , Sanati, Hamid-Reza Cardiovascular Intervention Research Center -Rajaie Cardiovascular, Medical, and Research Center -Iran University of Medical Sciences, Tehran, I.R. Iran , Firouzi, Ata Cardiovascular Intervention Research Center -Rajaie Cardiovascular, Medical, and Research Center -Iran University of Medical Sciences, Tehran, I.R. Iran , Zahedmehr, Ali Cardiovascular Intervention Research Center -Rajaie Cardiovascular, Medical, and Research Center -Iran University of Medical Sciences, Tehran, I.R. Iran , Kiani, Reza Cardiovascular Intervention Research Center -Rajaie Cardiovascular, Medical, and Research Center -Iran University of Medical Sciences, Tehran, I.R. Iran , Doaee, Mahdyie Community Medicine Specialist - Iran University of Medical Sciences, Tehran, I.R. Iran. , Nikpajouh, Akbar Rajaie Cardiovascular - Medical, and Research Center - Iran University of Medical Sciences, Tehran, I.R. Iran
Abstract :
Background: Diabetes is the cause of 25% of all the cases of coronary artery disease and
myocardial infarction (MI). One of the best interventions for coronary artery occlusion
treatment is percutaneous coronary intervention (PCI). In PCI, myocardial area size, lesion
morphology, cardiac function, renal failure, and other comorbidities are very important.
Evaluation of the periprocedural MI prevalence is significant for comparing diabetic and
nondiabetic patients.
Methods: This cross-sectional study was done in Rajaie Cardiovascular, Medical, and Research
Center by convenience sampling in 2009. PCI was performed on 605 patients, comprising
171 diabetic and 434 nondiabetic patients. Our information form included the type of
contrast, arterial access, diabetic type, blood glucose control, lab tests, and number of
coronary artery lesions. The incidence of postprocedural MI was evaluated by the
measurement of CK-MB. The data were then entered into SPSS before they were described
and analyzed. The χ2 test and the t-test were employed for data evaluation.
Results: The incidence of post procedural MI was 2.9% in the diabetics and 2.5% in the
nondiabetics. Moreover, 71.7 % of the patients were diabetic and 28.3% were nondiabetic.
The blood glucose level was controlled in 12.6% of the study population, while it was not
controlled in 87.4%. The P value for the comparison of periprocedural MI between the
diabetic and nondiabetic patients was 0.788. All of the 5 diabetic patients with
periprocedural MI belonged to the uncontrolled blood glucose group. The highest frequency
of MI was in the patients with 3-vessel PCI (P=0.027).
Conclusions: No significant statistical difference was observed regarding postprocedural MI
between the diabetic and nondiabetic patients. Preprocedural MI was more frequent in the
patients with 3-vessel PCI. PCI is a safe procedure with a low incidence rate of
postprocedural MI.
Keywords :
Myocardial infarction , Stent , troponin , Arterial access , Coronary artery disease , Percutaneous coronary intervention