Author/Authors :
Safarpoor, Gholamreza Department of Cardiac Surgery - Faculty of Medical Sciences - Farshchian Heart Center - Hamadan University of Medical Sciences, Hamadan, IR Iran , Emami, Farzad Department of Cardiology - Faculty of Medical Sciences - Farshchian Heart Center - Hamadan University of Medical Sciences, Hamadan, IR Iran , Shams, Amir Department of Cardiac Surgery - Faculty of Medical Sciences - Farshchian Heart Center - Hamadan University of Medical Sciences, Hamadan, IR Iran , Keshavari, Sheida Department of Cardiac Surgery - Faculty of Medical Sciences - Mashhad University of Medical Sciences, Mashhad, IR Iran , Moeinipour, Aliasghar Department of Cardiac Surgery - Faculty of Medical Sciences - Mashhad University of Medical Sciences, Mashhad, IR Iran , Manafi, Babak Department of Cardiac Surgery - Faculty of Medical Sciences - Farshchian Heart Center - Hamadan University of Medical Sciences, Hamadan, IR Iran
Abstract :
Background: The acute occlusion of the left main coronary artery (LMCA) in the absence of the
collateral circulation is extremely rare, but it remains a catastrophic and mostly fatal entity due
to myocardial infarction with severe cardiogenic shock and arrhythmias.
Methods: We evaluated 2 patients with an acute or acutely evolving occlusion of the LMCA
undergoing coronary artery bypass grafting (CABG).
Results: The in-hospital mortality rate was 50%. Revascularization was achieved with on-pump CABG
in both patients.
Conclusions: The total occlusion of the LMCA represents a unique clinical condition. The LMCA
occlusion with shock is regarded as a class IA indication for acute surgical revascularization.
Nonetheless, emergent percutaneous coronary intervention (PCI) may be an effective method to
acutely revascularize these patients. Additionally, aggressive post-PCI care—including intraaortic
balloon pumps, extracorporeal membrane oxygenation, CABG, and ventricular support
devices—may be required to improve patient survival.
Keywords :
Left main coronary artery obstruction , Myocardial infarction , Cardiogenic shock , Early revascularization , Coronary artery bypass surgery