The Long-Term Effects of Chemo Radiotherapy on Oral Health and Dental Development in Childhood Cancer: A Case Report

The improvement in survival and local control measures in children with neoplasm in thehead and neck region may lead to increased iatrogenic adverse effects of treatment. Theaim of this study was to report a new case of the long-term effects of chemoradiotherapyon oral health and dental development in a patient treated for Hodgkin's disease at an earlyage. In this case report, a 26-year-old female is presented, who at the age of 5 years receivedchemotherapy and radiotherapy for Hodgkin's disease in the neck region. The patientconsulted the Department of Oral Medicine because of dental changes and tooth lossdespite adequate dental care and oral hygiene. Clinical examination revealed loose teethand inflamed gingiva of the mandible, x-ray showed premature root resorption, V-shapedand shortened roots and alveolar bone loss. After examination, the patient was referred forextracting the mandibular teeth and then wassent to the prosthetics department. Therefore,in order to decrease dental treatment sequelae in patients who have had cured malignantdisease, these cases should have life-long dental care and follow-up.