Title of article :
Saccharin: a green, economical and efficient catalyst for the one-pot, multi-component synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives and 1H-pyrazolo [1,2-b] phthalazine-5,10-dione derivatives and substituted dihydro-2-oxypyrrole
Author/Authors :
Mohamadpour, Farzaneh Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Taher Maghsoodlou, Malek Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Heydari, Reza Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Lashkari, Mojtaba Faculty of Science Velayat University, Iranshahr
Abstract :
In this method, we have reported the catalytic ability of saccharin as a green, eco-friendly catalyst for the multi-component efficient synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives and 1H-pyrazolo [1,2-b]phthalazine-5,10-dione derivatives and substituted dihydro-2-oxypyrrole with excellent yields and short reaction times. This present methodology has notable benefits such as green, inexpensive and non-toxic catalyst, one-pot, environmental benign nature, solvent-free conditions, simplicity of operation with no necessity of chromatographic purification steps and eco-friendly.
Keywords :
Green synthesis , Saccharin , Eco-friendly , 3,4-Dihydropyrimidinone , 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives , Dihydro-2-oxypyrrole substituted , Multi-component reaction
Journal title :
Astroparticle Physics
