Author/Authors :
Sayyahfar, Shirin Department of Paediatrics - Ali Asghar Children Hospital - Iran University of Medical Sciences - Tehran, IR Iran , Karimi, Abdollah Paediatric Infection Research Centre - Shahid Beheshti University of Medical Sciences - Tehran, IR Iran , Fahimzad, Alireza Paediatric Infection Research Centre - Shahid Beheshti University of Medical Sciences - Tehran, IR Iran , Gharib, Atoosa Department of Pathology - Imam Hosein Hospital - Shahid Beheshti University of Medical Sciences - Tehran, IR Iran
Abstract :
Introduction: Anaplastic large cell lymphoma is a subset of non-Hodgkin lymphoma and an unusual disease in children.
Case Presentation: Herein we have reported a 7- year- old girl with a large necrotic skin ulcer on the chest caused by systemic form of anaplastic large-cell lymphoma and simultaneous active toxoplasmosis diagnosed by PCR on lymph node specimen. There were few reports showing a role for toxoplasma infection to cause some malignancies such as lymphoma in adults.
Conclusions: Based to our knowledge, this has been the first report of simultaneous systemic anaplastic large cell lymphoma and active toxoplasmosis, documented by positive PCR on tissue biopsy in a child. This case report has suggested more attention to the accompanying Toxoplasma gondii infection as a probable cause of some types of lymphomas.
