Author/Authors :
Ketabi, Mohammad Ali Faculty of dentistry - Aja University of medical science, Tehran , Shanavazi, Maryam Faculty of dentistry - Aja University of medical science, Tehran , Fekrazad, Reza Department of periodontics - Faculty of dentistry - AJA University of medical science, Tehran , Tondnevis, Farbod Faculty of Biomedical Engineering - Amirkabir University of Technology (Tehran Polytechnic), Tehran , Keshvari, Hamid Faculty of Biomedical Engineering - Amirkabir University of Technology (Tehran Polytechnic), Tehran , Raz, Majid Faculty of Biomedical Engineering - Amirkabir University of Technology (Tehran Polytechnic), Tehran , Sadeghi, Ali Faculty of Biomedical Engineering - Amirkabir University of Technology (Tehran Polytechnic), Tehran , Bajelani, Kourosh Faculty of Biomedical Engineering - Amirkabir University of Technology (Tehran Polytechnic), Tehran , shahrousvand, Mohsen Department of polymer engineering and color technology - Amirkabir University of technology, Tehran , Zalli, Ali Reza Shohada Tajrish Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Mohseni, Gholamreza Shahid Beheshti University of Medical Sciences, Tehran , Abolhasani, Mohammad Mahdi Department of Nanotechnology & Advanced Materials - Materials & Energy Research Center, Karaj
Abstract :
Regeneration and engineering of functional new tissues containing the neural network have
great importance. Progression of neural network into the dental tissue has a crucial role in
dental tissue regeneration. In the present study polymer-ceramic blended scaffolds containing
different weight percentages of carbon nanotube in poly caprolactone nanofiber matrix were
fabricated. Morphological, mechanical and electrical properties of the prepared scaffolds have
been characterized. Results showed that the sample containing 5 weight % of carbon nanotube
had the smallest mean fiber diameter (50 - 300 nm) and the highest mechanical behavior. Also,
its electrical conductivity was suitable to be used in nerve tissue scaffolds. mical properties as
scaffold for neural tissue engineering. The static culture of the Schwann cells on the prepared
scaffolds indicated that increasing weight percentage of carbon nanotube into the polycaprolactone
matrix up to the 5 wt. % enhanced cell viability.
Keywords :
Nerve Tissue Engineering , Carbon Nano Tube , Polycaprolactone , Nano Fiber , Schwann Cells , Characterization
