Author/Authors :
Seddighi, Afsoun Shahid Beheshti University of Medical Sciences, Tehran , Nikouei, Amir Shahid Beheshti University of Medical Sciences, Tehran , Seddighi, Amir Saied Shahid Beheshti University of Medical Sciences, Tehran , Asadpour, Mohammad Department of Neurology - Amol University of Medical Sciences, Amol , Masoudian, Noushin Department of Neurology - Semnan University of Medical Sciences, Semnan , Samaie, Afshin Department of Neurology - Semnan University of Medical Sciences, Semnan
Abstract :
Gene therapy consists of the introduction of genetic material into cells for a therapeutic purpose.
The understanding of the basics of the molecular and cellular mechanisms in disease treatments
has resulted in the development of high-tech gene transfer materials with improved therapeutic
efficacy. Based on the results of more than 2000 clinical trials to date, gene therapy is going
to be included in standard treatment approaches in some specific diseases. Also, gene therapy
has been highly improved in central and peripheral nervous system diseases. This review tried
to focus on techniques and approaches in brain tumors and nervous system’s gene therapy
strategies and will discuss about associated problems and potential future in management of
inherited or acquired neurological disorders.
Keywords :
Gene therapy , Brain , Treatment , Nervous system
