Title of article :
NEURO-VASCULAR CONFLICT AS CAUSATIVE FACTOR IN IDIOPATHIC TRIGEMINAL NEURALGIA
Author/Authors :
Mumtaz, Ali Department of Neurosurgery - Postgraduate Medical Institute - Lady Reading Hospital - Peshawar, Pakistan , Khan, Hamzullah Department of Neurosurgery - Postgraduate Medical Institute - Lady Reading Hospital - Peshawar, Pakistan
Abstract :
Trigeminal neuralgia is one of the most unbearable pain syndromes in one or more branches of trigeminal
nerve. The basic pathology is still poorly understood 1 . Two divergent view points, central versus peripheral
have been presented to explain the possible
mechanism 2. In spite of numerous favorable reports,
the neurovascular conflict theory remains contravertical
3. Nevertheless, whether or not, neurovascular
compression is accessory or predominant in the mechanism
of trigeminal neuralgia is not yet determined.
Although neurovascular compression and global
atrophy of the root, a focal arachnoid thickening and
angulated root on crossing over the petrous ridge
have been observed. Yet, neurovascular conflict has
made responsible as the main cause of this neuralgia 4.
This lead to focal demylination of the nerve due to its
pulsatile compression. Demylination result in short
circuiting of neuronal flow and hence trigeminal neuralgia
5.
Present study was therefore designed as to appreciate
neurovascular conflict as causative agent in idiopathic
trigeminal neuralgia.
Keywords :
NEURO-VASCULAR CONFLICT , CAUSATIVE FACTOR , TRIGEMINAL NEURALGIA
Journal title :
Astroparticle Physics