• Title of article

    RELATIONSHIPS OF SERUM LEPTIN CONCENTRATION WITH INSULIN, GLUCOSE, HbA1c LEVELS an‎d INSULIN RESISTANCE IN OVERWEIGHT POST-MENOPAUSAL DIABETIC WOMEN

  • Author/Authors

    Taghdir, Maryam Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Djazayeri, Abolghasem Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Djalali, Mahmoud Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Eshraghian, Mohammadreza Department of Biostatistics - School of Health - Tehran University of Medical Sciences, Tehran , Rajab, Asadollah , Sadrzade Yegane, Haleh Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Ashourpour, Mahkameh Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Sepandi, Mojtaba Department of Epidemiology and Biostatistics - School of Health - Jondishapour University of Medical Sciences, Ahwaz

  • Pages
    6
  • From page
    175
  • To page
    180
  • Abstract
    BACKGROUND: Leptin, the product of the ob gene, could have a role in the pathogenesis of obesity and non-insulin dependent diabetes mellitus (NIDDM). The aim of this study was to investigate relationships between serum leptin concentration and insulin, glucose, HbA1c levels and insulin resistance in diabetic women. METHODS: We studied 45 diabetic women and 45 healthy women (controls) who aged 45-60 years and had BMI of 25-30 kg/m2. Serum leptin, insulin, HbA1c, fasting blood sugar and insulin resistance were determined in the two groups. RESULTS: There was a significant positive correlation between leptin and insulin (r = 0.295, P = 0.049) and insulin resistance (r = 0.329, P = 0.027) in controls but non-significant correlation between leptin and HbA1c and fasting blood sugar were observed in the two groups. CONCLUSION: This study did not document any significant relationship between serum leptin and insulin, glucose, HbA1c and insulin resistance in diabetic women.
  • Keywords
    Type 2 Diabetes Mellitus , Leptin , Insulin
  • Journal title
    Astroparticle Physics
  • Serial Year
    2010
  • Record number

    2444944

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2444944