Author/Authors :
Zaree, R Department of Ophthalmology - Farabi Eye Hospital - Medical Sciences/University of Tehran, Tehran , Eslami, Y Department of Ophthalmology - Farabi Eye Hospital - Medical Sciences/University of Tehran, Tehran , Fakhraie, G Department of Ophthalmology - Farabi Eye Hospital - Medical Sciences/University of Tehran, Tehran , Ghannadi, F General practitioner , Varmazyar, R General practitioner
Abstract :
There are reports from different countries that some types of glaucoma are associated with
blood groups. This cross-sectional study was performed on 400 glaucomatous patients [100 patients in
each group of Primary open angle glaucoma (POAG), chronic angle closure glaucoma (CACG),
pseudoexfoliative glaucoma (PEXG) and primary congenital glaucoma (PCG)] and 400 blood donors as
control group to assess the association between blood groups and glaucoma. All patients underwent
ABO and Rh blood group testing. The prevalence of blood group A was 30% in the control group, 27%
in POAG, 33% in CACA, 38% in PEXG and 36% in PCG. The prevalence of blood group B was 24%
in the control group, 19% in POAG, 20% in CACG, 15% in PEXG and 34% in PCG (P < 0.025). The
prevalence of blood group AB was 8% in the control group, 9% in POAG, 5% in CACG, 12% in
PEXG, and 8% in PCG. The prevalence of blood group O was 38% in the control group, 45% in POAC,
42% in CACG, 35% in PEXG and 22% in PCG (P < 0.001). The prevalence of Rh+ was 88% in the
control group, 84% in POAG, 87% in CACG, 86% in PEXG and 87% in PCG. Compared to control
group, blood group B was more prevalent and blood group O was less prevalent in PCG. There was no
association between other types of blood groups (ABO and Rh) and PCG. There was no association
between blood groups (ABO and Rh) and other types of glaucoma.
