Author/Authors :
Mobini, Maryam Department of Internal Medicine - Diabetes Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences , Akha, Ozra Department of Internal Medicine - Diabetes Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences , Fakheri, Hafez Department of Gastroenterology, Inflammatory Gut and Liver Research Center, Mazandaran University of Medical Sciences , Majidi, Hadi Department of Radiology, Orthopedic Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences , Fattahi, Sanam Medical Student - Faculty of Medicine, Mazandaran University of Medical Sciences
Abstract :
Pachydermoperiostosis (PDP) is a rare disorder characterized
by pachydermia, digital clubbing, periostitis, and an excess
of affected males. It is the primary form of hypertrophic
osteoarthropathy (HOA) and there are some rare associations
of PDP with other disorders. Here we describe a patient with
Crohn’s disease associated with PDP. A 26-year-old man, who
was a known case of Crohn’s disease, referred with diffuse
swelling in the upper and lower limbs and cutis verticis gyrata
since 7 years ago. PDP was suspected and endocrinological
and radiological studies were conducted for the evaluation
of underlying disease. He was prescribed celecoxib, lowdose
prednisolone, and pamidronate to control the swelling,
periostitis, azathiopurine, and mesalazine according to
gastrointestinal involvement. In conclusion, it is important to
identify this condition since a misdiagnosis might subject the
patient to unnecessary investigations.
Keywords :
Pachydermoperiostosis , Cutis verticis gyrata , Crohn’s disease , Pamidronate
