Author/Authors :
Ramezani, Fatemeh Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Keshavarz, Ali Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Jalali, Mahmud Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Eshraghian, Mohamadreza Department Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran , Chameri, Maryam Department of Nutrition and Biochemistry - School of Health - Tehran University of Medical Sciences, Tehran
Abstract :
INTRODUCTION: Obesity increased reactive oxygen species generation that it result in oxidative
injury on lipids profile and lipoproteins that all of which insert atherosclerotic effect. Nutritional
intervention by means of a hypocaloric diet could produce protective effects against the
redox unbalance. In this context, the aim of this intervention trial was to estimate the ability of
weight loss to improve oxidative stress biomarkers related to lipids peroxidation and lipid profile
and apoproteins concentrations of serum in obese women.
METHODS: Thirties eight obese women, 15-45 years old, with body mass index (BMI <30
kg/m2 were recruited. The obese women were assigned to energy-restricted dietary treatments
for 12 week. Before and after nutritional intervention and 10% weight reduction, anthropometric
measurements were taken and fasting blood was drawn. Plasma levels of (MDA) determined
with TBAR and triglyceride, total cholesterol and HDL cholesterol.
Keywords :
MDA , lipid profile , obese woman , Weight loss
