Title of article :
Assessment of Spirometric Indices in Patients with Type 2 Diabetes in Imam Hussein Hospital, Shahroud, Iran (2016-2017)
Author/Authors :
Tayarani, Alireza Student Research Committee - School of Medicine - Shahroud University of Medical Sciences , Moazamian, Dina Student Research Committee - School of Medicine - Shahroud University of Medical Sciences , Farsi, Morteza Surgical Technologist - Ehyagaran Teb Mashhad Instituition, Mashhad , Salimi, Masoume Dept. of Endocrinology - Tehran University of Medical Sciences
Abstract :
Background: Diabetes mellitus is the most prevalent metabolic
disorder. Previous related studies have shown that, lungs are target
organs in diabetic micro-angiopathy. The present study was designed
to investigate the spirometric indices in patients with type 2 diabetes
referred to the outpatient clinic of Imam Hussein hospital in Shahroud,
Iran.
Methods: This comparative study included 50 patients with type 2
diabetes and 50 non-diabetic subjects who were matched in terms of
weight, age, and sex, and were referred to the Diabetes clinic of Imam
Hussein hospital in Shahroud, Iran. MIR SPIROLAB III spirometer
was used for spirometric tests to obtain FEV1, FVC, PEFR, and FEF
25-75. Decrease in these indices is determinant of pulmonary
complications. Indices were compared between two groups. The
relationships between some variables like glycated hemoglobin
(HbA1c) and type of their treatment with the severity of spirometric
disturbances were also assessed.
Results: The average age was equal to 56.3 years old (with SD of 6.3
years) and 58.3 years old (with SD of 6.3 years), respectively in nondiabetic
and diabetic group. Comparison of the FEV1, FVC, PEFR,
and FEF 25-75 indices between diabetic and non-diabetic groups
showed a significant difference (P.V<0.05). No significant difference
was found in the FEV1/FVC ratio. According to the Pearson
correlation formula, there was a significant association between
decreased spirometric indices and increased concentration of Hb A1C
(-.630, -.635 and-.374 for FEV1, FVC, and PEFR, respectively). There
was no association between decreased concentration of FEV1/FVC
and increased HbA1c. Conclusions: The findings of the study revealed that, there was a
significant decrease in pulmonary functions in the diabetic group.
Impaired pulmonary function can be detected in early stages of
diabetes and studying the pulmonary function can be easily preformed.
Accordingly, screening lungs function should be carried out regularly,
as well as integrating in other routine examinations and screening
tests.
Keywords :
Diabetes , Spirometry , Pulmonary disease , Imam Hussein hospital
