Author/Authors :
Shahabi, Javad Heart Failure Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Emkanjoo, Zahra Cardiac Electrophysiology Research Center - Rajaie Cardiovascular Medical and Research Center - Iran University of Medical Sciences, Tehran, Iran , Haghjoo, Majid Cardiac Electrophysiology Research Center - Rajaie Cardiovascular Medical and Research Center - Iran University of Medical Sciences, Tehran, Iran , Alizadeh, Abolfath Cardiac Electrophysiology Research Center - Rajaie Cardiovascular Medical and Research Center - Iran University of Medical Sciences, Tehran, Iran , Fazelifar, Amirfarjam Cardiac Electrophysiology Research Center - Rajaie Cardiovascular Medical and Research Center - Iran University of Medical Sciences, Tehran, Iran , Madadi, Shabnam Cardiac Electrophysiology Research Center - Rajaie Cardiovascular Medical and Research Center - Iran University of Medical Sciences, Tehran, Iran , Kamali, Farzad Cardiac Electrophysiology Research Center - Rajaie Cardiovascular Medical and Research Center - Iran University of Medical Sciences, Tehran, Iran , Sharifi, Mehrana Cardiac Electrophysiology Research Center - Rajaie Cardiovascular Medical and Research Center - Iran University of Medical Sciences, Tehran, Iran , Karimian, Zahra Cardiac Electrophysiology Research Center - Rajaie Cardiovascular Medical and Research Center - Iran University of Medical Sciences, Tehran, Iran , Yadegarfar, Ghasem Heart Failure Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran
Abstract :
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia, and its
prevalence increases with advancing age. Pulmonary vein isolation is a standard approach in
drug refractory paroxysmal AF which could be performed by cryoballoon ablation (CBA). We
tried to evaluate its efficacy and safety in Iranian patients with AF.
METHODS: From 2015 to 2017, 97 patients with paroxysmal and persistent AF were enrolled in
our observational historical cohort study. They were visited 1 and 6 months post-procedure in
order to assess the efficacy (recurrence) and safety. Recurrence was defined as 30 seconds of
arrhythmia on their 48-hours Holter monitoring.
RESULTS: Ninety-seven patients enrolled in the study, 64 (66.0%) of them were men, and their
mean age was 55 ± 12 years. Hypertension was reported in 41 patients (42.3%), as the most
common cardiac risk factor. 71 patients (73.2%) patients with paroxysmal AF and 15 patients
(15.5%) with persistent AF underwent the procedure. After 6 months, recurrence was
documented in only 17 patients (17.5%), and 82.5% of the patients were free from the
recurrence. Post-procedural complication was detected only in 3 patients (3.1%).
CONCLUSION: In our study, the mid-term success and safety of CBA in patients with paroxysmal
AF was showed. CBA is a safe and effective method in paroxysmal AF, and even in some cases
with persistent AF.
