Author/Authors :
Sajjadi, Firoozeh Heart Failure Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Mohammadifard, Noushin Hypertension Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Maghroun, Maryam Interventional Cardiology Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Shirani, Fatemeh Food Security Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Karimi, Simin Cardiac Rehabilitation Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Taheri, Marzie Interventional Cardiology Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Sarrafzadegan, Nizal Isfahan Cardiovascular Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran
Abstract :
BACKGROUND: Lifestyle modification is the most important strategy for control of obesity and
overweight. Obestatin and adiponectin are the biomarkers of obesity. Thus, this study was
performed to examine the effect of educational and encouragement interventions and lifestyle
modifications on obesity anthropometric as well as obestatin and adiponectin levels.
METHODS: This semi-experimental study was conducted on a subsample of TABASSOM study.
Participants were 41 overweight and obese children and adolescents aged 6-18 years old and 45
overweight and obese adults aged 19-65 years old. Anthropometric characteristics including
height, weight, waist and hip circumferences, and body fat percentage (BFP) were measured at
the first and after one year at the end of study. We implemented some educational and
encouragement interventions regarding dietary modification and physical activity during the
study. Obestatin and adiponectin levels were measured at the first and end of study by enzymelinked
immunosorbent assay (ELISA) method.
RESULTS: The study did not show significant effect on anthropometric characteristics such as
body mass index (BMI) and waist circumference (WC). BFP decreased significantly in boys, total
children and adolescent group, and waist-to-hip ratio (WHR) decreased significantly only in
adolescent boys after 1 year (P < 0.050).
CONCLUSION: Educational and encouraging interventions and lifestyle modifications could lead
to decrease of body WHR and BFP in adolescent boys. This is helpful in controlling the
increasing rate of obesity.
Keywords :
Adiponectin , Obestatin , Adolescents , Children , Adults , Obesity , Overweight
