Author/Authors :
Rezaei, Farshid Infectious Diseases Specialist - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Avijgan, Majid Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, , Salehi, Hasan Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Yazdani, Mohammad Reza Assistant Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Meidani, Mohsen Assistant Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Babak, Anahita Community and Preventive Medicine Specialist - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Javadi, Abbas Ali Associate Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Ataei, Behrooz Associate Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Khorvash, Farzin Associate Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Rostami, Mojtaba Associate Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Mostafavizadeh, Kamyar Associate Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , Emami Naeini, Alireza Associate Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences , sherkat, Roya Associate Professor - Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences
Abstract :
BACKGROUND: During August 2009, novel H1N1 influenza virus began causing illness in Isfahan. Since rates of hospitalization
and mortality due to the disease have varied widely in different countries, we described the clinical, radiologic,
and demographic features of H1N1 hospitalized patients in a hospital in Isfahan.
METHODS: This cross-sectional study was conducted in Alzahra Hospital during September 2009 to February 2010.
Totally, 216 patients with confirmed, probable, or suspected cases of 2009 influenza A (H1N1) were admitted.
RESULTS: Most patients were women (50.5%). Mean age of patients was 26.6 ± 19.5 years. The most common complains
on admission were respiratory symptoms (91.6%, n= 198), fever (88.4%, n = 191), myalgia (65.7%, n = 142). In
addition, 120 patients (56%) had at least one underlying medical disorder. Thirty-six patients (16.7%) died. Mortality
was higher in children under 5 years old (10/36, 10%) and female cases (63.9% of died patients). Predicting variables
affecting mortality were intensive care unit (ICU) admission and procalcitonin (PCT) > 0.5. Antiviral treatment was
prescribed for 200 (92.5%) of the 216 patients.
CONCLUSIONS: Based on the findings of the present study, novel H1N1 influenza is highly prevalent among the youth.
Moreover, it causes a relatively high morbidity rate. Therefore, people need to be encouraged to have vaccination
against 2009 H1N1. Early diagnosis and treatment is related to less admission and shorter duration of hospitalization.
