Author/Authors :
Kashinakunti, Sangappa Virupaxappa Associate Professor - Department of Biochemistry, S.N. Medical College Bagalkot, Karnataka, India , Kollur, Pampareddy Assistant Professor - Department of Biochemistry, D. Y. Patil Medical College Kolhapur, Maharashtra, India , Kallaganada, Gurupadappa Shantappa Professor and HOD - Department of Biochemistry, S. Nijalingappa Medical College Bagalkot, Karnataka, INDIA , Rangappa, Manjula Assistant Professor - Department of Community Medicine, S.N. Medical College Bagalkot, Karnataka, India , Ingin, Jagadish Basavaraj Professor and HOD - Department of Biochemistry, M.R. Medical College Gulbarga, Karnataka. India
Abstract :
BACKGROUND: It is a well-known fact that there is increased oxidative stress and decreased serum antioxidant levels in
smokers than in non-smokers. In this study, the aim was to compare the serum levels of malondialdehyde (MDA), a
lipid peroxidation product and vitamin C, an antioxidant, between non- smokers (Group A) and chronic smokers
(Group B) and also between chronic smokers (Group B) and chronic smokers with acute myocardial infarction
(AMI) (Group C).
METHODS: Thirty six non-smokers and 36 chronic smokers appropriately matched with AMI patients were selected.
Thirty six smokers with AMI were selected from Hanagal Kumareshwara hospital, Bagalkot, Karnataka, India. Fasting
blood sample was collected in group A and group B. In AMI patients, blood sample was collected before any intervention.
Serum levels of MDA and vitamin C were estimated. Statistical analysis was done by t test using SPSS version 11.
The p< 0.05 was considered statistically significant. All the results were expressed as mean ± SD.
Keywords :
Chronic smokers , Myocardial infarction , MDA , Vitamin C
