Title of article :
ENDOLARYNGEAL NEUROFIBROMA
Author/Authors :
Doroudinia, A Department of ENT-Head and Neck Surgery - ENT-Head and Neck Surgery Research Cente - Hazrat-E-Rasoul Hospital - Iran University of Medical Sciences - Tehran, Iran , Izadi, F Department of ENT-Head and Neck Surgery - ENT-Head and Neck Surgery Research Cente - Hazrat-E-Rasoul Hospital - Iran University of Medical Sciences - Tehran, Iran , Arbabi, M.D Department of ENT-Head and Neck Surgery - ENT-Head and Neck Surgery Research Cente - Hazrat-E-Rasoul Hospital - Iran University of Medical Sciences - Tehran, Iran , Ahmadzad-Asl, M Department of Clinical Researches - Nikan Health Researchers Institute - Tehran, Iran
Abstract :
Neurofibromatosis is a benign neurogenic tumor, originating from Schwann cells of the
nerve sheath. This tumor forms a round, white mass on the course of the involved nerve. It occurs
sporadically or in association with von Recklinghausen’s disease. Laryngeal involvement is a rare
occasion that affects women more than men (F/M ratio 3:2). The most common symptoms are
hoarseness, dyspnea and dysphagia. The most common sites of origin are arytenoids and aryepiglottic
folds. Because of benign nature of this tumor, conservative surgery is recommended as the management
of choice. Only few cases of laryngeal involvement have been reported in literature and this article
presents two cases of laryngeal neurofibroma with brief review of literatures. Both cases presented with
submucosal, non-ulcerated, endolaryngeal mass with signs and symptoms of airway compromise. In
both cases surgical approach was endolaryngeal conservative surgery with CO2 laser.
Keywords :
CO2 laser , neurofibromatosis , endolaryngeal tumor , Neurofibroma
Journal title :
Astroparticle Physics
