Title of article :
Disseminated Mycobacterium tuberculosis in an Infant with AIDS
Author/Authors :
Masoumi Asl, Hossein Department of Pediatrics - Shiraz University of Medical Sciences, Shiraz , Alborzi, Abdolvahab Professor Alborzi Clinical Microbiology Research Center, Shiraz , Sadeghi, Esmaeel Department of Pediatrics - Shiraz University of Medical Sciences, Shiraz
Abstract :
Disseminated Mycobacterium tuberculosis with involvement of liver, spleen, and bone marrow is a nonspecific and rare complication
in human immunodeficiency virus (HIV) infected infants. Here, we report a six month old girl with fever, recurrent infections, bilateral
axilary lymphadenitis, hepatomegaly, huge splenomegaly, and failure to thrive. The infant and her mother had positive enzyme
immunoassay (EIA) and Western blot.
HIV DNA PCR test of the infant was positive with subtype A (A1) in genotyping. A positive bone marrow aspirate staining for acid fast
bacilli and PCR test on culture revealed Mycobacterium tuberculosis.
Keywords :
disseminated Mycobacerium tuberculosis , infant , HIV/AIDS
Journal title :
Astroparticle Physics