Author/Authors :
Ghafari, M.H Department of Anesthesiology - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Akrami, M. Department of Anesthesiology - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Sadeghi, M Department of Anesthesiology - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Ghoreishinejad, M Department of Anesthesiology - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran
Abstract :
Toxic reactions to local anesthetics may occur due to over dose, accidental intravenous
injections or rapid systemic uptake of the drugs. But there have been few reports on toxicity due to
displacement of epidural catheters after an initial correct insertion and performance of a test dose. Here
we present a case of local anesthetics toxicity due to possible displacement of the epidural catheter
during APR (Ant-post Colporrhaphy) surgery. The patient’s level of consciousness decreased at the end
of surgery. She demonstrated CNS and cardiovascular toxicity due to local anesthetics. Consequently
the patient was intubated and transferred to ICU, where she received mechanical ventilation along with
other supportive treatments such as inotropic and antiepileptic drugs. We concluded that supportive
therapy is the treatment of choice for such cases.