Author/Authors :
Khorvash, Farzin Nosocomial Infectious Diseases Research Center, Isfahan University of Medical Sciences, Isfahan , Abdi, Fatemeh Infectious Diseases Research Center, Isfahan University of Medical Sciences, Isfahan , Ataei, Behrooz Infectious Diseases Research Center, Isfahan University of Medical Sciences, Isfahan , Fattahi Neisiani, Hamed Assistant of Heart Diseases, Isfahan University of Medical Sciences, Isfahan, , Hasanzadeh Kashani, Hessam Department of Physiology - School of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada , Narimani, Tahmineh Department of Microbiology, Isfahan University of Medical Sciences, Isfahan
Abstract :
This study aimed to determine the frequency of nasal carriage and antibiotic susceptibility profile of Staphylococcus
aureus (S. aureus) among healthy young adults who referred to premarital screening clinics. METHODS: A cross-sectional
study including 158 adults (79 men and 79 women) was conducted at health care centers, Isfahan, Iran, during February-August
2008. Nasal swabs from anterior nares of healthy adults were cultured and tested for S. aureus. Antibiotic susceptibility testing was
performed on Muller-Hinton Agar using disc diffusion method according to Clinical Laboratory Standards Institute (CLSI).
RESULTS: The prevalence of S. aureus nasal carriage was 26.6%. Resistance to penicillin had the highest rate. The isolates demonstrated
higher sensitivity to vancomycin, clindamycin, and rifampicin. In addition, twenty-two S. aureus isolates had intermediate resistance
to antibiotics. CONCLUSIONS: The importance of implementing strategies to eliminate nasal carriage of S. aureus to prevent
the spread of infection is highlighted. Effective strategies in this field are thus strongly recommended.
