Author/Authors :
Mottaghi, Tayebeh Food Security Research Center, Isfahan University of Medical Sciences , Ghiasvand, Reza Food Security Research Center, Isfahan University of Medical Sciences, , Maghsoudi, Zahra Food Security Research Center, Isfahan University of Medical Sciences, , Khorvash, Fariborz Neurology Research Center, School of Medicine, Isfahan University of Medical Sciences , Gholamreza Askari Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences , Maracy, Mohammad Reza Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences , Iraj, Bijan Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan
Abstract :
Migraine is common worldwide. In recent years, vitamin D deficiency has been determined as a global health problem.
A few studies have shown inverse relationship between serum vitamin D levels and headache. Thus, in this study, we assessed relationship
between serum vitamin D levels with migraine. Materials and Methods: The present study was a cross‑sectional. Seventy‑six migraine
patients aged 10-61 years were included. The multiple linear regression was used to show association between serum 25‑0H‑D3 and
migraine. Adjustments were performed for age, sex, waist circumference, body mass index (BMI), number of chronic diseases, and
education level. Results: The positive weak relationship was observed between serum vitamin D and headache diary result (P = 0.042,
r = 0.19). But, no significant relationship was observed between serum vitamin D and migraine severity (P = 0.741). Conclusion: High
levels of serum 25‑OH‑D3 was related to higher headache diary result. After adjustment for confounding variables, this significant
association remained. No significant relationship was shown between serum vitamin D and migraine severity.
