Title of article
Detection of colistin sensitivity in clinical isolates of Acinetobacter baumannii in Iran
Author/Authors
Vakili, Bahareh Infectious Diseases and Tropical Medicine Research Center , Fazeli, Hossein Infectious Diseases and Tropical Medicine Research Center , Ataei, Behrooz Infectious Diseases and Tropical Medicine Research Center , Shoaei, Parisa Nosocomial Infection Research Center , Khorvash, Farzin Nosocomial Infection Research Center , Yaran, Majid Acquired Immunodefi ciency Research Center, Isfahan University of Medical Sciences, Isfahan , Khaleghi, Moj Department of Biology, Faculty of Science, Shahid Bahonar University of Kerman
Pages
4
From page
67
To page
70
Abstract
Nosocomial infection caused by Acinetobacter baumannii has emerged as a serious problem world-wide. Finding the
suitable drug is an important priority. Th e aim of this study was to determine colistin (polymyxin E) resistance in clinical isolates
of A. baumannii from intensive care units (ICUs) of Al Zahra Hospital. Materials and Methods: Sixty isolates of A. baumannii
from patients hospitalized in ICU (Al Zahra Hospital, Isfahan University of Medical Sciences [IUMS]) were studied. All isolates
of A. baumannii were tested for colistin susceptibility by Eopsilometer test (E-test). Results: Of the 60 isolates 57, (95%) were
multidrug resistant (MDR) and 76.6% (46/60) were highly resistant. Th e rate of colistin resistant with the E-test method was 11.6%
(7/60). Conclusion: As the frequency of resistance to colistin is low, it can be used as an easily available drug for treatment of MDR
A. baumannii strains, which are susceptible to colistin.
Keywords
Acinetobacter baumannii , colistin resistance , multidrug resistant organism
Journal title
Astroparticle Physics
Serial Year
2014
Record number
2446802
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