Author/Authors :
Vakili, Bahareh Infectious Diseases and Tropical Medicine Research Center , Fazeli, Hossein Infectious Diseases and Tropical Medicine Research Center , Ataei, Behrooz Infectious Diseases and Tropical Medicine Research Center , Shoaei, Parisa Nosocomial Infection Research Center , Khorvash, Farzin Nosocomial Infection Research Center , Yaran, Majid Acquired Immunodefi ciency Research Center, Isfahan University of Medical Sciences, Isfahan , Khaleghi, Moj Department of Biology, Faculty of Science, Shahid Bahonar University of Kerman
Abstract :
Nosocomial infection caused by Acinetobacter baumannii has emerged as a serious problem world-wide. Finding the
suitable drug is an important priority. Th e aim of this study was to determine colistin (polymyxin E) resistance in clinical isolates
of A. baumannii from intensive care units (ICUs) of Al Zahra Hospital. Materials and Methods: Sixty isolates of A. baumannii
from patients hospitalized in ICU (Al Zahra Hospital, Isfahan University of Medical Sciences [IUMS]) were studied. All isolates
of A. baumannii were tested for colistin susceptibility by Eopsilometer test (E-test). Results: Of the 60 isolates 57, (95%) were
multidrug resistant (MDR) and 76.6% (46/60) were highly resistant. Th e rate of colistin resistant with the E-test method was 11.6%
(7/60). Conclusion: As the frequency of resistance to colistin is low, it can be used as an easily available drug for treatment of MDR
A. baumannii strains, which are susceptible to colistin.
