Title of article :
Nanotechnology; its significance in cancer and photodynamic therapy
Author/Authors :
Gaeeni, M.R Laser and Optics Research School - Nuclear Science and Technology Research Institute - North Karegar, Tehran , Sasani Ghamsari, m Laser and Optics Research School - Nuclear Science and Technology Research Institute - North Karegar, Tehran , Tohidian, M Faculty of Medicine, Tehran University of Medical Sciences, Tehran , Majles Ara, M.H Photonic Laboratory, Physics Department, Kharazmi University, Tehran
Abstract :
In the last decade, developments in nanotechnology have provided a new field in medicine called “Nanomedicine”. Nanomedicine
has provided new tools for photodynamic therapy. Quantum dots are approximately spherical nanoparticles that have
attracted broad attention and have been used in nanomedicine applications. Quantum dots have high molar extinction
coefficients and photoluminescence quantum yield, narrow emission spectra, broad absorption, large effective stokes shifts.
Quantum dots are more photostable and resistant to metabolic degradation. These photosensitizing properties can be used
as photosensitizers for Photodynamic Therapy. Photodynamic Therapy has been recommended for its unique characteristic,
such as low side effect and more efficiency. Therefore, nanomedicine leads a promising future for targeted therapy in cancer
tumor. Furthermore, Quantum dots have recently been applied in Photodynamic Therapy, which will be addressed in this
review letter. Also this review letter evaluates key aspects of nano-particulate design and engineering, including the
advantage of the nanometer scale size range, biological behavior, and safety profile.
Keywords :
Cancer tumor , Nanomedicine , Photodynamic therapy (PDT) , Quantum dots (QDs
Journal title :
Astroparticle Physics