Title of article :
Flow Cytometry of CD64, HLA-DR, CD25, and TLRs for Diagnosis and Prognosis of Sepsis in Critically Ill Patients Admitted to the Intensive Care Unit: A Review Article
Author/Authors :
Mahmoodpoor, Ata Anesthesiology Research Team - Tabriz University of Medical Sciences, Tabriz , Paknezhad, Pouya Emergency Medicine Research Team - Tabriz University of Medical Sciences, Tabriz , Shadvar, Kamran Anesthesiology Research Team - Tabriz University of Medical Sciences, Tabriz , Hamishehkar, Hadi Drug Applied Research Center - Tabriz University of Medical Sciences, Tabriz , Movassaghpour, Ali Akbar Hematology and Oncology Research Center - Tabriz University of Medical Sciences, Tabriz , Sanaie, Sarvin Aging Research Institute - Tabriz University of Medical Sciences, Tabriz , Ghamari, Ali Akbar Anesthesiology Research Team - Tabriz University of Medical Sciences, Tabriz , Soleimanpour, Hassan Emergency Medicine Research Team - Tabriz University of Medical Sciences, Tabriz
Abstract :
Sepsis is an important health problem with a high burden on health systems. Finding new aspects of immune system function in sepsis showed a new role for flow cytometry in the diagnosis of sepsis. We made a review on the role of CD64, HLA-DR, CD25, and TLRs as more useful flow cytometric tools in diagnosing sepsis, both in adults, and neonates. According to our results, we concluded that for diagnosis and treatment of the septic, flow cytometry can play an important role so that it can be used as a novel method in individualized treatment of septic patients based on their immune system situation.
Keywords :
Flow Cytometry , Sepsis , CD 64 , HLA-DR , CD 25 , Toll Like Receptor
