Author/Authors :
Jayadevappa, Honnali Department of Chemistry - Sahyadri Science College - Shimoga - Karnataka-577203, India , Veerachar Harisha, Kammar Department of PG Studies and Research in Industrial Chemistry - Kuvempu University - Jnana Sahyadri - Shankaraghatta-577451 - Shimoga - Karnataka, India , Eshwaraswamy Kumara Swamy, Bahaddurghatta Department of PG Studies and Research in Industrial Chemistry - Kuvempu University - Jnana Sahyadri - Shankaraghatta-577451 - Shimoga - Karnataka, India , Siddappa Ganesh, Pattan Department of PG Studies and Research in Industrial Chemistry - Kuvempu University - Jnana Sahyadri - Shankaraghatta-577451 - Shimoga - Karnataka, India
Abstract :
Poly (alanine) modified carbon paste electrode (CPE) was fabricated for the determination of 5-amino salicylic acid (5-ASA) by cyclic voltammetric technique. The poly (alanine) modified CPE exhibited a high sensitivity towards the oxidation of 5-ASA. The effect of scan rate was found to be surface-controlled diffusion process and the concentration study was conducted between the range of 20-180 μM. The limit of detection (3 S/M) and limit of quantification (10 S/M) were calculated and found to be 0.23 μM and 0.76 μM respectively. Because of high sensitivity in the electro-oxidation, the fabricated poly (alanine) modified CPE can be used as a promising electrochemical sensor for the determination of 5-ASA in both commercial as well as in pharmaceutical samples.
Keywords :
Electropolymerisation , 5-amino salicylic acid , Poly (alanine) , Cyclic voltammetry , Carbon paste electrode
