Title of article :
Simultaneous Determination of Dopamine, Acetaminophen and Xanthine by Modified Carbon Ceramic Micro-Electrode with Nanosized LaFe0.2Ni0.8O3 Perovskite
Author/Authors :
Noroozifar, Meissam Department of Chemistry - University of Sistan and Baluchestan - Zahedan, Iran , Tohidinia, Masoumeh Department of Chemistry - University of Sistan and Baluchestan - Zahedan, Iran , Sabbaghi, Najmeh Department of Chemistry - University of Sistan and Baluchestan - Zahedan, Iran , Shaybani, Shervin Department of Chemistry - University of Sistan and Baluchestan - Zahedan, Iran
Abstract :
For the first time a cheap and simple modified carbon ceramic micro-electrode
(MCCME) with nanosized LaFe0.2Ni0.8O3 perovskite has been developed for simultaneous
determination of dopamine (DA), acetaminophen (AC) and xanthine (XN). The
electrochemical response characteristics of the MCCME toward DA, AC and XN were
investigated by cyclic voltammetry, differential pulse voltammetry and chronoamperometry.
Under the optimum conditions, linear calibration plot was obtained over the range 6.66-131,
9.99-131 and 3.99-115 μM with detection limits 2.1, 3.2 and 1.3 μM for DA, AC and XN,
Respectively. The value of diffusion coefficient was found to be 9×10-6, 6.3×10-5 and 4.8×10-
4 cm2s-1 for DA, AC and XN, respectively. The analytical performance of this sensor has been
evaluated for simultaneous detection of these three analysts in human serum samples.
Keywords :
Nanosized LaFe0.2Ni0.8O3 perovskite , Carbon ceramic micro-electrode , Simultaneous determination
Journal title :
Astroparticle Physics
