Title of article :
EVALUATION OF A BREAKFAST AS SCREENING TEST FOR THE DETECTION OF GESTATIONAL DIABETES
Author/Authors :
Eslamian, L Department of Perinatology Obstetrics and Gynecology - Shariati Hospital - School of Medicine - Medical Sciences - University of Tehran , Ramezani, Z Department of Perinatology Obstetrics and Gynecology - Shariati Hospital - School of Medicine - Medical Sciences - University of Tehran
Abstract :
A standard breakfast was evaluated as a screening test (BT) for gestational diabetes in a
case-control study. Blood sugar (BS) was measured 1 hour after a breakfast that had 50gr simple sugar
and was designed based on women preferences. In the same women glucose challenge test (GCT, 50gr
1hour glucose screening test) was performed one week later in randomized sequential. Cutoff values
for both tests was 130 mg/dl. For both or one positive test GTT (100gr-oral glucose tolerance test)
was performed. Sensitivity and specificity; optimal cutoff and concordance of both tests with GTT were
calculated by X2, receiver operating characteristic (ROC) curve and kappa test. 41 women (29.3%) had
positive GCT and 28 women (20%) had positive BT. 12 women (8.57%) had positive GTT. For BT and
GCT, a sensitivity of 83.3% and 91.7% and specificity of 85.9% and 76.6% with cutoff level < 130
mg/dl at 60 minute were found respectively. Optimal cutoff for BT and GCT were 130 mg/dl and 135
mg/dl respectively. Concordance of GTT with GCT and BT was 0.429 and 0.432, respectively.
Standard breakfast can be used as an alternative method for assessing carbohydrate intolerance in
pregnancy with same physiological response, better compliance and low cost.
Keywords :
Breakfast test , Gestational diabetes mellitus (GDM) , Screening , GTT
Journal title :
Astroparticle Physics