Title of article :
Hydrothermal Synthesis of Cobalt- Doped Hydroxyapatite Nanoparticles: Structure, Magnetic Behaviour, Bioactivity and Antibacterial Activity
Author/Authors :
Yazdani, N School of Metallurgy and Materials Engineering - Iran University of Science and Technology - Tehran, Iran , Javadpour, J School of Metallurgy and Materials Engineering - Iran University of Science and Technology - Tehran, Iran , Eftekhari Yekta, B School of Metallurgy and Materials Engineering - Iran University of Science and Technology - Tehran, Iran , Hamrang, M School of Metallurgy and Materials Engineering - Iran University of Science and Technology - Tehran, Iran
Abstract :
This study focuses on the physical, magnetic, biological and antibacterial behavior of cobalt-doped hydroxyapatite
(HAp) powder samples. Pure and cobalt- doped HAp nanoparticles were synthesized by hydrothermal method.
Calcium nitrate, di- ammonium hydrogen phosphate and cobalt nitrate were used as precursor materials. The synthesized
powders were characterized using x-ray diffraction pattern (XRD), fourier transform infrared spectroscopy (FTIR), eld
emission scanning electron microscopy (FESEM), vibrating sample magnetometer (VSM), raman spectroscopy as well as
MTT assay and cell adhesion test. Disc diffusion method was used to investigate antibacterial activity of the samples. The
results conrmed the substitution of Ca by Co ions in the HAp lattice. In addition, this substitution induced size reduction
and morphology change in HAp particles. All cobalt substituted HAp powder samples displayed paramagnetic properties,
as opposed to the diamagnetic behavior observed in the pure HAp samples. In addition, these nanoparticles exhibited cell
adhesion, cell viability and antibacterial activity against S.aureus bacteria.
Keywords :
Antibacterial activity , Paramagnetic , Hydrothermal , Cobalt- doped hydroxyapatite , Hydroxyapatite
Journal title :
Astroparticle Physics