Author/Authors :
Esfandiar, Nasrin Pediatric Nephrology Research Center - Faculty of Medicine - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Sharifian, Mostafa Pediatric Nephrology Research Center - Faculty of Medicine - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Dalirani, Reza Pediatric Nephrology Research Center - Faculty of Medicine - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Alaei, Fariba Pediatric Cardiology Department - Faculty of Medicine - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Khalilian, Mohammad Reza Pediatric Cardiology Department - Faculty of Medicine - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Alaei, Mastaneh Pathology- Blood Transfusion Research Center - High Institute for Research and Education in Transfusion - Tehran, Iran
Abstract :
This is a report of a 44-month-old baby girl diagnosed as a case of atypical hemolytic uremic syndrome (aHUS) presenting with hematuria, periorbital edema, anemia, thrombocytopenia, and hypertension lacking any history of previous bloody diarrhea. She was treated with plasma infusion followed by plasmapheresis and peritoneal dialysis. After two months, she was discharged in remission undergoing periodic plasmapheresis. Four months later, she was visited for fatigue, tachypnea, and palpitation. Cardiac evaluation revealed dilated cardiomyopathy with an ejection fraction of 15-20%. She was hospitalized and treated with inotropes and diuretics; one week later, she was discharged in a favorable condition. After six months follow-up, she showed an acceptable renal and cardiac state. It seems that cardiomyopathy can occur as a late and rare complication of HUS. We recommend cardiac evaluation for all patients with HUS at its presentation and in later follow-ups.
