Author/Authors :
Ghane Sharbaf, Fatemeh Nephrology Department - Dr. Sheikh Hospital - Mashhad University of Medical Sciences - Mashhad, Iran , Maleknejad, Mahmood Nephrology Department - Dr. Sheikh Hospital - Mashhad University of Medical Sciences - Mashhad, Iran , Moshari, Jalil Nephrology Department - Dr. Sheikh Hospital - Mashhad University of Medical Sciences - Mashhad, Iran , Azarfar, Anosh Nephrology Department - Dr. Sheikh Hospital - Mashhad University of Medical Sciences - Mashhad, Iran , Esmaeili, Mohammad Nephrology Department - Dr. Sheikh Hospital - Mashhad University of Medical Sciences - Mashhad, Iran , Zabolynejad, Nona Dr. Sheikh Hospital - Mashhad University of Medical Sciences - Mashhad, Iran , Rezayi Yazdi, Zahra Ghaem Hospital - Mashhad University of Medical Sciences - Mashhad, Iran
Abstract :
Renal amyloidosis is a late manifestation of chronic juvenile rheumatoid arthritis (JRA) and usually manifests during the first 10 to 15 years after the onset of JRA. We hereby report a boy with JRA-related renal amyloidosis who presented with nephrotic syndrome in early childhood. Amyloidosis was associated with a 6-year history of juvenile rheumatic arthritis (JRA). Diagnosis of renal amyloidosis was confirmed by the deposition of Congo red positive amyloid fibrils within the glomeruli. Polarized light microscopy showed the classic green birefringence appearance.
