Title of article :
Olive Leaves Extract Effects on Sperm Quality Following ExperimentallyInduced Diabetes in Rats
Author/Authors :
Alirezaei ، Masoud - Lorestan University , Alirezaei ، Masoud - Lorestan University , Kheradmand ، Arash - Lorestan University , Kheradmand ، Arash - Lorestan University , Salahi ، Pouya - Lorestan University , Salahi ، Pouya - Lorestan University , Azizi ، Afsaneh - Lorestan University , Azizi ، Afsaneh - Lorestan University
Abstract :
Background: The experimental model of streptozotocine (STZ)induced diabetes explains changes in the male reproductive system as part of the disease. Objective: The aim of the present study was to evaluate the olive leaf extract effects on STZinduced diabetes and to examine its modulatory effects on sperm quality. Methods: Twenty adult male Sprague–Dawley rats were divided into four equal groups: the first group served as untreated control. Groups 2, 3 and 4 of rats were injected STZ (65 mg/kg). The animals which exhibited blood glucose levels higher than 250 mg/dl by days 46, were considered as diabetic rats. Groups 3 and 4 received olive leaf extract (100 and 150 mg/kg, orally) and vehicle to the control and diabetic rats (group 2) for 10 consecutive days. Results: Glycated haemoglobin percentage (%HbA1c) as a diabetic index significantly decreased in the animals ingested by the 150 mg/kg of the extract compared to the diabetic group (P
Journal title :
Iranian Journal of Veterinary Medicine
Journal title :
Iranian Journal of Veterinary Medicine
