Lung Resuscitation with Perfluorocarbons Vapor: A Future Outlook

Hypoxia is a major concern for human health. Multiple new techniques were proposed for tissue oxygenation in different variety of patients. Clark Jr. et al. presenting their article titled “Fluorovent: A New Perfluorocarbon for Liquid Ventilation”, at a symposium in neonatology, in 1995, described the scientific importance for perfluorocarbons which would be ideally suited for use in liquid ventilation and artificial blood as well. In 1966, Clark published his article that demonstrated that spontaneously breathing mice could survive when submerged in perfluorocarbons (PFCs) under normobaric conditions. The first trial of liquid ventilation in preterm neonates in 1989 showed the feasibility and potential of liquid ventilation in humans. So liquid ventilation became as an alternative ventilation strategy for respiratory distress.