Hashimoto Encephalopathy with Sensory Polyneuropathy: A Case Report

Hashimoto encephalopathy is an autoimmune disease characterized by an increase in antithyroid antibodies in the serum of patients with multiple neuropsychological symptoms. We report a case with lower level of antibody and fairly response to corticosteroid; however, clinical presentation, brain magnetic resonance imaging findings and the negative results of other diseases confirmed Hashimoto encephalopathy diagnosis. First, a relatively good corticosteroid response was seen but after one weak, the patient withdrew her drug and got back with a corticosteroid resistant progressive attack one month later. Our case had a mild increase in antithyroid antibodies and pure sensory polyneuropathy and did not show significant response to corticosteroid therapy. Can antithyroid antibodies titers be a marker of corticosteroid treatment response? this should be investigated in the future studies.