Polycystic Ovary Syndrome Combined with Type II Polyglandular Autoimmune Syndrome

A 30-year-old woman with a 20-year history of type 1 diabetes referred to our clinic with the complaints of facial acne, hirsutism, and irregular menstrual cycles (hirsutism was identified in physical examination). On biochemical analysis, high serum levels of anti- TPO and DHEA-S were detected. Based on ultrasonographic findings indicative of thyroiditis and positive anti-TPO test, the diagnosis of Hashimoto s thyroiditis was made. A diagnosis of Polycystic Ovary Syndrome (PCOS) was confirmed later according to the Rotterdam criteria (revised 2003). The patient received metformin and insulin for 3 months and her menstrual cycles became regular.