Title of article :
A THREE DIMENSIONAL HTLV-1 MODEL WITH INTRACELLULAR AND IMMUNE ACTIVATION DELAYS
Author/Authors :
SHAMSARA ، ELHAM - FERDOWSI UNIVERSITY OF MASHHAD (FUM) , SHAMSARA ، JAMAL - MASHHAD UNIVERSITY OF MEDICAL SCIENCES , AFSHARNEZHAD ، ZAHRA - FERDOWSI UNIVERSITY OF MASHHAD (FUM)
Abstract :
In this paper, a three dimensional mathematical model for HTLV-1 infection with intracellular delay and immune activation delay is investigated. By applying the frequency domain approach, we show that time delays can destabilize the HAM/TSP equilibrium, leading to Hopf bifurcations and sta- ble or unstable periodic oscillations. At the end, numerical simulations are illustrated
Keywords :
CTL response , Graphical Hopf bifurcation theorem , Fre quency domain , Delay divterential equation , HTLV , 1 infection
Journal title :
journal of mahani mathematical research center
Journal title :
journal of mahani mathematical research center
