Title of article
Genotype Characterization of Human Hydatid Cyst Isolates From Patients in Karaj, Iran, Using COX1 Gene Sequence
Author/Authors
Salimi ، Maryam - Alborz University of Medical Sciences , Miahipour ، Abolfazl - Alborz University of Medical Sciences , Zibaei ، Mohammad - Alborz University of Medical Sciences , Rezaie ، Sasan - Tehran University of Medical Sciences
Pages
3
From page
27
To page
29
Abstract
Background: Cystic echinococcosis is a main zoonotic infection. It can cause serious clinical problems for human health around the world. Genotypic specification of Echinococcus granulosus in human is important due to control and prevention programs. Objective: In this investigation, genetic characteristics of human isolates of E. granulosus in Karaj, Iran, were studied. Materials and Methods: In this review, 3 isolates of surgically removed hydatid cysts were obtained from patients in Shahid Madani hospital, Karaj, Iran in 2014. DNA was extracted from the protoscolex of the cyst, and polymerase chain reaction (PCR) assay was done on the COX1 gene. Results: DNA fragments were sequenced and the results were aligned and analyzed. Among the isolates, 3 (100%) were E. granulosus (G1) strain. Conclusion: The G1 genotype was the most superior strain from human isolates of hydatid cyst in Karaj.
Keywords
COX1 , Genotype , Human Hydatid Cyst , Karaj
Journal title
International Journal of Enteric Pathogens
Serial Year
2019
Journal title
International Journal of Enteric Pathogens
Record number
2467700
Link To Document