Author/Authors :
Varshini, M Departments of Oral Pathology and Microbiology - A.B. Shetty Memorial Institute of Dental Sciences - Nitte (Deemed to be University) - Mangalore - Karnataka, India , Salian, Varsha Departments of Oral Pathology and Microbiology - A.B. Shetty Memorial Institute of Dental Sciences - Nitte (Deemed to be University) - Mangalore - Karnataka, India , Shetty, Pushparaja Departments of Oral Pathology and Microbiology - A.B. Shetty Memorial Institute of Dental Sciences - Nitte (Deemed to be University) - Mangalore - Karnataka, India , Krishnan, Shalini Departments of Oral and Maxillofacial Surgery - A.B. Shetty Memorial Institute of Dental Sciences - Nitte (Deemed to be University) - Mangalore - Karnataka, India
Abstract :
In India, oral squamous cell carcinoma accounts for 90%–95% of oral malignancies. The WHO
classifies spindle cell carcinoma (SpCC) under malignant epithelial tumors of squamous cell
carcinoma (SCC) and is a rare entity accounting for only 1% of SCCs. It is an aggressive biphasic
neoplasm exhibiting high mortality rate owing to increased metastasis and recurrence which signifies
the need for recognition and treatment of this perplexed tumor. We present a case of maxillary
SpCC where histopathological evaluation alone was indecisive, requiring immunohistochemistry
for confirmation of the diagnosis.