Synthesis of Hydroxyapatite Containing some Trace Amounts Elements in Simulated Body Fluids

Spherical-like hydroxyapatite (HA, Ca10(PO4)6(OH)2) particles were prepared by the co-precipitation method in a simulated physiological environment. The effect of calcining temperature, calcining time and the Ca/P ratio of the initial feeding on the morphology and crystallinity of HA were investigated in detail. Interestingly, while the Ca/P ratio of the initial feeding is 1.80, the obtained HA powders calcined at 800 °C for 2 h contain trace amounts of Na and Mg ions, and the (Ca+Na+Mg)/P ratio is equal to 1.66, which is close to the stoichiometric ratio 1.67 of HA. And a better route with shorter reaction time for the synthesis of HA containing trace amounts of Na and Mg elements was acquired.