Author/Authors :
Vosoughifar, Mohammad Young Researchers and Elite Club - Central Tehran Branch, Islamic Azad University, Tehran, Iran , Mohammadian Asiabar, Bahman Department of chemistry - Payame Noor University, Tehran, Iran , Karimi, Mohammad Ali Department of chemistry - Payame Noor University, Tehran, Iran , Tavallali, Hossein Department of chemistry - Payame Noor University, Tehran, Iran , Khoshroo, Alireza Pharmaceutical Sciences Research Center - School of Pharmacy - Kermanshah University of Medical Sciences, Kermanshah, Iran , Rahimi-Nasrabadi, Mehdi Faculty of Pharmacy - Baqiyatallah University of Medical Sciences, Tehran, Iran
Abstract :
Spherical-like cobalt aluminate nanoparticles were successfully synthesized by sol-gel method by new capping agent. The X-ray diffraction spectrum confirms the pure phase cobalt aluminate nanoparticles. The presence of stretching and bending vibrations of Co-O and Al-O confirmed by FT-IR analysis in the cobalt aluminate nanoparticles. The mean size of cobalt aluminate nanoparticles were examined by TEM techniques between 20 to 40 nm. The synthesized nanoparticle was used for determination of acyclovir. In the electrochemical section, the effects of pH, scan rate and Acyclovir concentration were studied. The peak current was linear with the acyclovir concentration in the range of 1μM to 30 μM and the detection limit was found to be 0.4μM.
Keywords :
Nanoparticles , Acyclovir , Sol-gel method , Cobalt aluminate
