X-Fe2O4-Buckypaper-Chitosan Nanocomposites for Nonenzymatic Electrochemical Glucose Biosensing

The exploitation of undemanding modifications needed for rising the sensitivity and functionality of nanobiosensors is still remaining a challenge. Conventional enzyme-based sensors propose favorably selective and sensitive determination of glucose at the outlay of low stability. Thus, promoting the comfortable, sensitive, rapid and consistent strategies play an impressive role for determining the human glucose level. Here, a new nanocomposite, X-Fe2O4- Buckypaper-Chitosan (X=Fe3O4, ZnFe2O4 and CuFe2O4), was scrutinized to find an appropriate substrate for nonenzymatic biosensing. The nanocomposites were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and Field emission scanning electron microscopy (FESEM). The average particle size of all nanoparticles was lower than 100 nm. The Cu-Fe2O4-buckypaper-chitosan composite has shown a significant electrochemical behavior compared with the other composites. The biosensor was applied to detect glucose with a linear range of 0.25×10−3–17×10−3 M and detection limit is 0.025 μM. The biosensor presented reasonable results for glucose at applied potential of 0.575 V with a fast response time (<4 s). This is the first research on the X-Fe2O4-Buckypaper-Chitosan biosensing application and its abovementioned sensing characteristics are comparable with those heretofore reported developments.